High Rate of β-Globin DNA Detection Validates Self-Sampling in Herpes Simplex Virus Shedding Studies

Conclusions: Human β-globin DNA detection rate was high, and the quantity obtained significantly increased with genital, but not oral HSV shedding. The high rate of β-globin DNA detection is consistent with high adherence to study procedures in longitudinal studies of genital herpes shedding. (Source: Sexually Transmitted Diseases)
MedWorm: Genital Herpes

Read More

Cholestanol-conjugated Sulfated Oligosaccharide PG545 Disrupts Lipid Envelope of Herpes Simplex Virus Particles.

Authors: Said JS, Trybala E, Görander S, Ekblad M, Liljeqvist JÅ, Jennische E, Lange S, Bergström T Abstract Herpes simplex virus (HSV) and many other viruses including HIV initiate infection of host cells by binding to glycosaminoglycan (GAG) chains of cell surface proteoglycans. Although GAG mimetics such as sulfated oligo- and polysaccharides exhibit potent antiviral activity in cultured cells, the prophylactic application of these inhibitors as vaginal microbicides failed to protect women on their exposure to HIV infection...

Read More

Non-healing genital herpes mimicking donovanosis in an immunocompetent man

We report a case of genital herpes manifesting as painless chronic non-healing genital ulcers with exuberant granulation tissue in an immunocompetent man. Owing to this morphology, the ulcers were initially mistaken for donovanosis. To the best of our knowledge, such a presentation of genital herpes in an immunocompetent individual has not been described previously. (Source: International Journal of STD and AIDS)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

MedWorm: Genital Herpes

Read More

Team of US Navy doctors suggests internet pornography may be fueling rise in sexual dysfunctions

A team of urologists, neuroscientists and psychiatrists from the US Navy has reported in a new review published in Behavioral Sciences that sexual difficulties appear to be increasing sharply among…
Sexual Health / STDs News From Medical News Today

Read More

Characteristics of Sexually Transmitted Infections among High-Risk HIV-Positive Patients Attending an Urban Clinic in Uganda

Conclusion: Clinical and microbiologically diagnosed STIs were diagnosed in nearly one-fourth of the HIV-positive high-risk population. HIV care programs should note our high rates of STIs among HIV-positive high-risk populations and consider routine screening and treatment algorithms for these populations in their own settings. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
MedWorm: Genital Herpes

Read More

Fatal Neonatal Herpes Simplex Infection Likely from Unrecognized Breast Lesions

Type 1 herpes simplex virus (HSV-1) is very prevalent yet in rare circumstances can lead to fatal neonatal disease. Genital acquisition of type 2 HSV is the usual mode for neonatal herpes, but HSV-1 transmission by genital or extragenital means may result in greater mortality rates. A very rare scenario is presented in which the mode of transmission was likely through breast lesions. The lesions were seen by nurses as well as the lactation consultant and obstetrician in the hospital after delivery of the affected baby but not recognized as possibly being caused by herpes. The baby died 9 days after birth with hepatic failure and disseminated intravascular coagulation...

Read More

Assisted-living facilities limit older adults’ rights to sexual freedom, study finds

Older adults in assisted-living facilities experience limits to their rights to sexual freedom because of a lack of policies regarding the issue and the actions of staff and administrators at these…
Sexual Health / STDs News From Medical News Today

Read More

Common virus’ link to breast cancer investigated

The most common virus to infect humans – EBV – plays a role in breast cancer. New research may have uncovered the mechanisms behind this relationship.
Sexual Health / STDs News From Medical News Today

Read More

Genital Herpes Simplex Virus Type 2 Shedding Among Adults With and Without HIV Infection in Uganda

Conclusions. HSV-2 shedding frequency and quantity are high among HSV-2–seropositive adults in sub-Saharan Africa, including persons with and those without HIV infection. Shedding rates were particularly high among men, which may contribute to the high prevalence of HSV-2 and early acquisition among African women. (Source: The Journal of Infectious Diseases)
MedWorm: Genital Herpes

Read More

Regardless of age, health conditions, many seniors not retired from sex

Despite societal perceptions that older adults’ love lives are ancient history, many seniors are anything but retired from sex, a new study suggests.
Sexual Health / STDs News From Medical News Today

Read More